Looking for a partner to scale outbound prospecting, fill your sales pipeline, and book more qualified meetings? Below are the best San Francisco B2B outbound sales agencies that specialize in outbound sales, appointment setting, and lead generation.
AltiSales is an outsourced SDR and sales development agency that offers fully managed SDR teams, appointment setting, outbound prospecting and SDR coaching. Their core work is running phone-first and multi-channel outbound sales programs - cold calling, cold email, LinkedIn and list building - so internal sales reps receive qualified meetings and a more predictable pipeline. They emphasize measurable outbound sales metrics, SDR training, and reducing customer acquisition cost via efficient outbound sales processes.
Highlights:
Check them out: https://www.altisales.com/

Demand Inc. is a San Francisco-based sales development and demand-generation firm that blends human SDRs with AI and data to run appointment-setting and outbound prospecting programs for B2B clients. They advertise outreach (email, phone, social), contact data enrichment, and campaign reporting designed to shorten sales cycles, surface intent signals, and deliver qualified leads and meaningful conversations with decision makers. Their messaging highlights pipeline acceleration and measurable outbound sales efforts.
Highlights:
Check them out: https://www.demandinc.co/

Upcall runs human-powered outbound calling and appointment-setting services (on-demand SDR / call teams). Their model is phone-first outbound sales calls + appointment setting, useful for teams that need immediate contact with cold prospects and quick handoffs to closers. Upcall emphasizes real-time reporting, call staffing, and dialing at scale for campaigns that require human conversations.
Highlights:
Check them out: https://www.upcall.com/

Tactical TeleSolutions (TTS) is a San Francisco call-center and B2B lead-generation agency that advertises appointment setting, outbound calling, list management and sales outsourcing from an SF address. They focus on phone-based outbound prospecting, scripted qualification, and handing off qualified meetings to internal sales reps so closers can focus on closing deals. TTS’s long-running local presence makes them a practical phone-first partner for Bay Area B2B outreach.
Highlights:
Check them out: https://www.ttstechnique.com/

Start Up And Fly advertises B2B appointment-setting and sales outsourcing among its services. They position themselves as a sales & growth partner for startups entering the U.S. market - building outbound sales processes (list building, cold outreach, appointment setting) and managing outbound sales reps to deliver qualified leads and scheduled discovery calls.
Highlights:
Check them out: https://startupandfly.com/

Martal Group is an international B2B outbound sales agency that's headquarted in a San Francisco office. They provide outsourced BDR/SDR teams, cold calling, email outreach and appointment setting targeted at decision makers across SaaS, cybersecurity and fintech verticals. Martal focuses on building pipelines through outbound prospecting and delivering qualified leads to closing teams. (Note: Martal is global but maintains a verified SF office.)
Highlights:
Check them out: https://martal.ca/

Callbox publishes a San Francisco market/lead-generation page and runs multi-channel outbound programs (cold calling, cold email, webinars, ABM). They offer outsourced SDR and appointment-setting services targeted to Bay Area accounts and emphasize generating high quality leads, tracking outbound sales metrics, and delivering a predictable sales pipeline for B2B sales teams.
Highlights:
Check them out: https://www.callboxinc.com/

Growth Rhino offers B2B outbound lead generation, cold email outreach, and appointment setting for SaaS and tech companies. Their approach mixes list building, outreach sequences and follow-ups to generate outbound leads and help sales teams secure qualified discovery calls.
Highlights:
Check them out: https://www.growthrhino.com/b2b-lead-genration-san-francisco

Leadium specializes in B2B appointment setting and SDR services and their case studies and client engagement pages include SF/Bay Area campaigns. They build outbound sales processes, manage outreach (cold calling + cold email + LinkedIn) and book meetings for client sales teams - helping shorten sales cycles and produce predictable pipeline.
Highlights:
Check them out: https://www.leadium.com/

Instead of going through the hassle of dealing with an agency, why not seamlessly streamline a grand majority of the process for a fraction of the cost?
Salesforge is a cold outreach tool built for not just more outbound sales activity but more closed deals and a predictable pipeline as well.

Salesforge's highlights include:
All agencies above can run effective outbound sales activities, but if your top priority is a plug-and-play outreach tool with multi-source hyper-personalization, premium deliverability, and campaigns optimized to the fullest potential - Salesforge is the better alternative.
Try the 14 day free trial today
Or in case you still haven’t found the right option for your business, feel free to take a look at our certified Forge Experts!


